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Constant-force photonic projectile for long-distance targeting delivery.

Authors :
Meng, Chun
Ren, Yu-Xuan
Lu, Fengya
Yu, Panpan
Zhou, Jinhua
Zhong, Min-Cheng
Source :
Nanophotonics (21928606); Dec2024, Vol. 13 Issue 26, p4805-4815, 11p
Publication Year :
2024

Abstract

Optically controllable delivery of microparticles excites interesting research and applications in various fields because of the noninvasive and noncontact features. However, long-distance delivery with a static low-power light source remains challenging. Here, the constant-force photonic projectile (CFPP) is employed to achieve long-distance delivery of microparticles with a low-power laser beam. The CFPP takes advantage of photon absorption to create a constant optical force within a large range, surpassing traditional tweezers. The concept of CFPP has been experimentally corroborated by remote control over micrometer-sized absorptive particles (APs) using a simple tilted focused beam. At the laser focus, strong photon absorption results in a large constant optical force that ejects the APs along the optical axis. Furthermore, the additional thermal convection field, which attracts particles from a distance into the working range of the CFPP, is utilized to collect the unbound APs for reuse. Finally, we demonstrate the concept of drug delivery by transporting a small microparticle onto a host particle at a remote location. The proposed CFPP provides a new perspective for drug delivery and heat-enhanced photodynamic therapy. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
21928606
Volume :
13
Issue :
26
Database :
Complementary Index
Journal :
Nanophotonics (21928606)
Publication Type :
Academic Journal
Accession number :
181289074
Full Text :
https://doi.org/10.1515/nanoph-2024-0484