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"Compositions And Methods For Inhibiting Viral Vector-Induced Inflammatory Responses" in Patent Application Approval Process (USPTO 20240384295).
- Source :
- Cancer Gene Therapy Week; 12/9/2024, p73-73, 1p
- Publication Year :
- 2024
-
Abstract
- A patent application by inventors from Harvard College aims to inhibit viral vector-induced inflammatory responses in gene therapy. The application focuses on recombinant viral genomes linked to inhibitory oligonucleotide sequences to prevent proinflammatory cytokine production. These vectors aim to enhance therapeutic gene expression while reducing the inflammatory response, potentially improving the efficacy of gene therapy treatments. The method involves administering these recombinant viral genomes intramuscularly, intravenously, or intravitreally to target specific tissues and inhibit toll-like receptor activation. [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 15436837
- Database :
- Complementary Index
- Journal :
- Cancer Gene Therapy Week
- Publication Type :
- Periodical
- Accession number :
- 181452749