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Distribution and Molecular Characterization of Antibiotic-Resistant Pseudomonas aeruginosa in Hospital Settings of Sulaymaniyah, Iraq.

Authors :
Ali, Seenaa Muhammed
Soor, Taib Ahmed Hama
Ahmed, Gashin Awat
Mhdin, Glena Aziz
Othman, Gulabakh Ali
Faiq, Sarkhel Mhamad
Source :
Polish Journal of Microbiology; Dec2024, Vol. 73 Issue 4, p467-473, 7p
Publication Year :
2024

Abstract

Pseudomonas aeruginosa is a significant pathogen in hospital settings, notorious for its role in hospital-acquired infections and its ability to develop resistance to multiple antibiotics. This study investigates the prevalence, distribution, and antibiotic resistance gene profiles of P. aeruginosa in seven hospitals in Sulaymaniyah City. A total of 300 samples were collected from various hospital surfaces including mops, sinks, medical equipment, beds, desks, and floors. Using bacteriological, biochemical, and molecular methods, 66 isolates were confirmed as Pseudomonas species, with 26 identified as P. aeruginosa. Antibiotic susceptibility testing revealed resistance rates of 23.3% to streptomycin, 13.6% to tobramycin, 22.7% to moxifloxacin, 21.2% to levofloxacin, and 22.7% to norfloxacin. Furthermore, the antibiotic resistance gene detection showed the presence of the bla<subscript>CTX-M</subscript>, bla<subscript>SHV</subscript>, qnrB, and bla<subscript>ACC-1</subscript> genes among the isolates. The study highlights a 22% contamination rate of hospital surfaces with Pseudomonas species, emphasizing the urgent need for enhanced infection control measures and targeted antimicrobial stewardship to manage and reduce the spread of multidrug-resistant P. aeruginosa. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
17331331
Volume :
73
Issue :
4
Database :
Complementary Index
Journal :
Polish Journal of Microbiology
Publication Type :
Academic Journal
Accession number :
181646373
Full Text :
https://doi.org/10.33073/pjm-2024-037