Findings from Duke University Reveals New Findings on Cardiovascular Diseases and Conditions [Cardiovascular Disease Pathogenicity Predictor (Cvd-pp): a Tissue-specific In Silico Tool for Discriminating Pathogenicity of Variants of Unknown...].

A recent study conducted at Duke University introduced a new tool, the Cardiovascular Disease Pathogenicity Predictor (Cvd-pp), designed to help differentiate between pathogenic and benign variants in cardiovascular disease genes. The model demonstrated high accuracy in prioritizing variants with changed clinical significance and in identifying individuals with dilated cardiomyopathy. This research could potentially aid in genetic diagnosis and large-scale genomic sequencing studies related to cardiovascular diseases. For more information, readers can refer to the original article published in Circulation: Genomic and Precision Medicine. [Extracted from the article]