A cross-species multimodal database of gene expression in cardiac hypertrophy.

The article discusses the creation of a multi-omics database called CHEERIO (Cardiac HypErtrophy gEne expRessIOn Database) that focuses on gene expression in cardiac hypertrophy and heart failure. The database allows for the exploration of gene expression in rodent and human models during different stages of cardiac hypertrophy and heart failure at various levels of resolution. The goal is to provide insight into the mechanisms that mediate the transition from cardiac hypertrophy to heart failure. The preprint has not been peer-reviewed and is available for further exploration at https://voelkerslab.shinyapps.io/CHEERIO/. [Extracted from the article]