Changzhi Medical College Researchers Publish New Studies and Findings in the Area of Gliomas (Identification of CDKN3 overexpression as a marker of poor prognosis and potential therapeutic target in low-grade glioma).

Researchers from Changzhi Medical College have identified CDKN3 overexpression as a marker of poor prognosis and a potential therapeutic target in low-grade glioma (LGG). The study analyzed data from the TCGA database and found that high CDKN3 expression in LGG patients was associated with poor survival outcomes. Further research revealed that CDKN3 silencing inhibited the proliferative capacity of LGG cells, suggesting a potential therapeutic strategy. This study enhances understanding of LGG biology and provides scientific evidence for targeting CDKN3 in treatment. [Extracted from the article]