VIGNETTES The Addition of Interferon Gamma to Oral Bexarotene Therapy With Photopheresis for Sézary Syndrome.

The article discusses the treatment of a 53-year-old white woman suffering from Sézary syndrome. Extracorporeal photopheresis, psoralen, UV-A, and interferon alfa-2b, 1.8 million units were injected subcutaneously three times weekly. Oral bexarotene in the quantity of 150 mg daily was also added to the medication. The patient's erythroderma and pruritus showed improvement but three months later the patient's erythroderma and pruritus recurred. Treatment with psoralen-UV-A was stopped.