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Oncogenes as Novel Targets for Cancer Therapy (Part IV): Regulators of the Cell Cycle and Apoptosis.
- Source :
- American Journal of PharmacoGenomics; 2005, Vol. 5 Issue 6, p397-407, 11p
- Publication Year :
- 2005
-
Abstract
- This is the final part of a four-part serial review on oncogenes and their potential use as targets for cancer therapy. Previous sections discussed various categories of oncogenes (growth factors, tyrosine kinases, intermediate signaling molecules, and transcription factors) and the advances made in various strategies being used to alter their actions. This part describes four oncogenes, MDM2, BCL2, XIAP, and Survivin, that are involved in regulation of the cell cycle and apoptosis. [ABSTRACT FROM AUTHOR]
- Subjects :
- ONCOGENES
CANCER treatment
PROTEIN-tyrosine kinases
TRANSCRIPTION factors
APOPTOSIS
Subjects
Details
- Language :
- English
- ISSN :
- 11752203
- Volume :
- 5
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- American Journal of PharmacoGenomics
- Publication Type :
- Academic Journal
- Accession number :
- 19099501
- Full Text :
- https://doi.org/10.2165/00129785-200505060-00006