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The TAK1-NLK-MAPK- related pathway antagonizes signalling between beta-catenin and transcription factor TCF.
- Source :
- Nature; 6/24/1999, Vol. 399 Issue 6738, p798, 5p, 4 Black and White Photographs, 12 Diagrams, 5 Graphs
- Publication Year :
- 1999
-
Abstract
- Presents research which showed that TAK1 activation stimulates NEMO-like kinase activity (NLK) and downregulates transcriptional activation mediated by beta-catenin and T-cell factor (TCF). Role of the Wnt signaling pathway in animal development; Signaling in Drosophila and in Caenorhabditis elegans; Effects of injecting NLK; Negative regulation by the TAK1-NLK-1-MAPK-like pathway of the Wnt pathway.
Details
- Language :
- English
- ISSN :
- 00280836
- Volume :
- 399
- Issue :
- 6738
- Database :
- Complementary Index
- Journal :
- Nature
- Publication Type :
- Academic Journal
- Accession number :
- 1985559
- Full Text :
- https://doi.org/10.1038/21674