In Vitro Degradation Behavior of Polyesteramide Copolymer Fiber Based on 6-Aminocaproic Acid, Adipic Acid, and 1,6-Hexane Diol.

In this work, a kind of aliphatic biodegradable polyesteramide (PEA) copolymer based on 6-aminocaproic acid, adipic acid, and 1,6-hexane diol was synthesized by melt polycondensation method, and was characterized by ¹H-NMR, FTIR and DSC. The PEA fiber was prepared by melt-spinning method. Tensile properties of the as-spun and hot-drawn fibers were also investigated. Hydrolytic degradation behavior of PEA copolymer chips and fibers were evaluated by weight loss in PBS solution with different pH value. The alkaline degradation behavior of fiber was also studied on change of diameter and surface morphology. During alkaline degradation, the PEA fiber underwent surface erosion. [ABSTRACT FROM AUTHOR]