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Primary nodal marginal zone B-cell lymphoma: clinical features and prognostic assessment of a rare disease.
- Source :
- British Journal of Haematology; Jan2007, Vol. 136 Issue 2, p301-304, 4p, 1 Chart, 1 Graph
- Publication Year :
- 2007
-
Abstract
- This study defined the clinical features and assessed the prognosis of 47 patients (17 males, 30 females, median age 63 years) with primary nodal marginal zone B-cell lymphoma. Forty-five per cent had stage IV disease. Hepatitis C virus serology was positive in 24%. According to the Follicular Lymphoma International Prognostic Index (FLIPI), 33% were classified as low-risk, 34% as intermediate-risk, and 33% as high-risk. The 5-year overall survival (OS) was 69%. In univariate analysis worse OS was associated with: FLIPI ( P = 0·02), age > 60 years ( P = 0·05) and raised lactate dehydrogenase ( P = 0·05). In multivariate analysis, only FLIPI predicted a worse OS ( P = 0·02). [ABSTRACT FROM AUTHOR]
- Subjects :
- LYMPHOMAS
B cell lymphoma
HEPATITIS C virus
PROGNOSIS
DIAGNOSTIC microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 00071048
- Volume :
- 136
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- British Journal of Haematology
- Publication Type :
- Academic Journal
- Accession number :
- 23848525
- Full Text :
- https://doi.org/10.1111/j.1365-2141.2006.06437.x