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The Incidence of First Provoked and Unprovoked Seizure in Pediatric Patients with and without Psychiatric Diagnoses.
- Source :
- Epilepsia (Series 4); Jun2007, Vol. 48 Issue 6, p1075-1082, 8p, 6 Charts
- Publication Year :
- 2007
-
Abstract
- Purpose: To estimate the rate of new-onset afebrile provoked and unprovoked seizure in a general pediatric population and subgroups of patients with and without psychiatric diagnoses other than attention deficit hyperactivity disorder (ADHD). Methods: A retrospective cohort study of 133,440 pediatric patients, between the ages of 6 and 17 years, and without history of seizure or prior use of anticonvulsant medications, with follow-up during 2003. The data source for this study was Ingenix's research database containing pharmacy and medical claims for members of a large US-based managed care organization. The main outcome measure was new-onset nonfebrile seizure. Incidence rates of seizure and 95% confidence intervals (CI) were calculated and expressed as rates per 100,000 person-years. Results: There were 132 new-onset provoked and unprovoked seizures in 78,423 person-years of follow-up among the general pediatric population sample. The incidence rate of seizure among the general pediatric population was 168 per 100,000 p-y (95% CI 141–200). The incidence rate of seizure among patients without psychiatric diagnoses was 149 per 100,000 p-y (95% CI 122–180). The incidence rate of seizure among patients with psychiatric diagnoses other than ADHD was 513 per 100,000 p-y (95% CI 273–878). There were increases in the incidence rates of seizure in all of the seizure risk factor groups, but this was more pronounced among males ages 6–12 with psychiatric diagnoses. Conclusions: The results of this study are consistent with previous reports showing that pediatric patients with psychiatric disorders have a higher incidence rate of seizure than the general pediatric population. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00139580
- Volume :
- 48
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Epilepsia (Series 4)
- Publication Type :
- Academic Journal
- Accession number :
- 25276543
- Full Text :
- https://doi.org/10.1111/j.1528-1167.2007.01108.x