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Two new 18-carbon norditerpenoid alkaloids from Aconitum sinomontanum.
- Source :
- Journal of Asian Natural Products Research; Sep2006, Vol. 8 Issue 6, p535-539, 5p
- Publication Year :
- 2006
-
Abstract
- Two new 18-carbon norditerpenoid alkaloids, sinaconitines A (1) and B (2), together with two known alkaloids, ranaconitine (3) and lappaconitine (4), were isolated from the roots of Aconitum sinomontanum. Their structures were elucidated on the basis of spectral evidences and X-ray crystallographic analysis for 1. Furthermore, the reversed <superscript>13</superscript>C NMR assignments for C-10 and C-13 of 3, 4, puberanine, puberanidine and demethyllappaconitine were revised. Compounds 1–4 were evaluated for cyclooxygenase-2 (COX-2) enzyme inhibitory activity. However, they did not show any inhibition at 10 μM. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10286020
- Volume :
- 8
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Journal of Asian Natural Products Research
- Publication Type :
- Academic Journal
- Accession number :
- 26658183
- Full Text :
- https://doi.org/10.1080/10286020500175643