Percentage of Gleason Pattern 4 and 5 Predicts Survival After Radical Prostatectomy.

The article focuses on a study on the effectiveness of combined percentage of Gleason patterns 4 and 5 in radical prostatectomy specimens in predicting cancer-specific survival among prostate cancer patients treated at Indiana University Medical Center in Indianapolis. The study analyzed various clinical and pathologic characteristics of the disease. It found that a higher combined percentage of Gleason patterns 4 and 5 was associated with older age, higher preoperative serum prostate-specific antigen level and lymph node metastasis.