New Eremophilenolactones from Senecio nemorensis.

Three new eremophilane sesquiterpenes were isolated from the MeOH extract of the roots of Senecio nemorensis. Their structures were identified as 8α-hydroxy-6β-(isobutanoyloxy)-1-oxoeremophila-7(11),9-dieno-12,8β-lactone (1), 6β,8β-dimethoxy-1-oxoeremophila-7(11),9-dieno-12,8α-lactone (2), and 10α-hydroxy-6β-(isobutanoyloxy)-1-oxoeremophila-7(11),8-dieno-12,8-lactone (3), respectively, based on spectroscopic data, including IR, EI-MS, HR-ESI-MS, and 1D- and 2D-NMR data. [ABSTRACT FROM AUTHOR]