Back to Search
Start Over
Control of atopic eczema with pimecrolimus cream 1% under daily practice conditions: results of a > 2000 patient study.
- Source :
- Journal of the European Academy of Dermatology & Venereology; Feb2008, Vol. 22 Issue 2, p195-203, 9p, 1 Black and White Photograph, 5 Charts, 4 Graphs
- Publication Year :
- 2008
-
Abstract
- Background Pimecrolimus cream 1% has been shown to effectively control atopic eczema (AE) when applied twice daily from the first signs or symptoms of AE until clearance. Moreover, pimecrolimus cream 1% has a favourable safety profile, lacking topical corticosteroid-related side-effects such as skin atrophy, making it particularly useful to treat delicate body regions (e.g. the face). Objective The objective of this naturalistic study was to monitor the safety, tolerability and efficacy of pimecrolimus when used in the long-term management of AE in a real-life setting. Methods A multicentre, open-label study was conducted in 2034 patients aged ≥ 3 months with mild to moderate AE for up to 12 months’ duration. Patients applied pimecrolimus cream twice daily, initiating treatment at first signs or symptoms of AE, continuing until clearance. Results Patients ( n= 1847; 91%) completed 3 months of the study. Treatment success (clear or almost clear AE) after 3 months of treatment was observed on the whole body in 59% of patients and on the face in 81% of patients. Disease improvement of whole body and face was seen in 77% and 63% of patients, respectively. Pruritus was absent or mild in 79% of patients. Pimecrolimus cream was well tolerated throughout the study. Conclusion In a daily practice setting, pimecrolimus cream 1% effectively and safely controls AE. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09269959
- Volume :
- 22
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Journal of the European Academy of Dermatology & Venereology
- Publication Type :
- Academic Journal
- Accession number :
- 28397319
- Full Text :
- https://doi.org/10.1111/j.1468-3083.2007.02368.x