Influence of Body Weight on the Performance of Glomerular Filtration Rate Estimators in Subjects With Type 2 Diabetes.

The article discusses a study which is aimed at identifying whether body weight may explain variability in performance between the Cockcroft-Gault and Modification of Diet in Renal Disease (MDRD) equations in patients newly diagnosed with type 2 diabetes. Accordingly, the study consisted of 293 subjects newly diagnosed with type 2 diabetes; 96% were Caucasian and the remainder of South Asian origin. It has been found that both formulae presented introduced significant biases and, in average terms, underestimated glomerular filtration rate (GFR).