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Role of AIM in Corynebacterium-induced granuloma formation in mice.
- Source :
- Comparative Hepatology; 2004 Supplement 1, Vol. 3, p1-3, 3p, 1 Diagram, 2 Graphs
- Publication Year :
- 2004
-
Abstract
- A conference paper on the role of apoptosis inhibitor expressed by macrophages (AIM) in Corynebacterium-induced granuloma formation in mice is presented. Results reveal the poor repopulation of natural killer T (NKT) cells in middle and late stages of granuloma formation in AIM-/-mice. Apoptosis of NKT cells and T cells was more prominent in AIM-/- mice. These findings indicate that AIM regulates NKT and T cell apoptosis and recruitment and plays a vital role in granuloma formation.
- Subjects :
- APOPTOSIS
MACROPHAGES
CUTIBACTERIUM acnes
GRANULOMA
KILLER cells
T cells
Subjects
Details
- Language :
- English
- ISSN :
- 14765926
- Volume :
- 3
- Database :
- Complementary Index
- Journal :
- Comparative Hepatology
- Publication Type :
- Academic Journal
- Accession number :
- 28742371