In Vivo Genome-Wide Expression Study on Human Circulating B Cells Suggests a Novel ESR1 and MAPK3 Network for Postmenopausal Osteoporosis.

The article presents a study which determines the significance of B cells in human bone metabolism and osteoporosis. Researchers have conducted a series of tests to identify differentially expressed genes that may illuminate the functions of B cells relating to the etiology and molecular genetic mechanisms of osteoporosis. Results reveal the significance of B cells in the etiology of osteoporosis and suggest a novel mechanism for postmenopausal osteoporosis.