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Humans Lack iGb3 Due to the Absence of Functional iGb3-Synthase: Implications for NKT Cell Development and Transplantation.
- Source :
- PLoS Biology; Jul2008, Vol. 6 Issue 7, pe172, 12p, 1 Color Photograph, 1 Diagram, 1 Chart, 5 Graphs
- Publication Year :
- 2008
-
Abstract
- Controversy surrounds the glycolipid iGb3. Our data show that humans do not express this lipid. This has important implications in natural killer T cell development, self-recognition, and transplantation. [ABSTRACT FROM AUTHOR]
- Subjects :
- T cells
ANTIGENS
IMMUNOGLOBULINS
CLINICAL trials
IMMUNOLOGY
Subjects
Details
- Language :
- English
- ISSN :
- 15449173
- Volume :
- 6
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- PLoS Biology
- Publication Type :
- Academic Journal
- Accession number :
- 33410124
- Full Text :
- https://doi.org/10.1371/journal.pbio.0060172