Pre-symptomatic Prediction of Illness in Mice Inoculated with Cowpox.

We describe here research directed towards early (presyndromic) diagnosis of infection. By using a mouse model and a multi-component blood protein diagnostic tool we detected cowpox infection several days in advance of overt symptoms with high accuracy. We provide details of the experimental design and measurement technique and elaborate on the long-range implication of these results. [ABSTRACT FROM AUTHOR]