Optimization of trehalose production by a novel strain Brevibacterium sp. SY361.

The article presents a study on the optimization of trehalose production by a novel strain of Brevibacterium sp. SY361 in submerged fermentation. It examines the increase trehalose productivity with the reactions of different chemical and physical parameters including carbon and nitrogen sources, inoculum level, and aeration and time-course of fermentation. It identifies concentration for trehalose production in the reaction of an optimal production medium containing 3% (w/v) glucose, 0.9% (v/v) corn steep liquor, and 0.5% (w/v) KH₂PO₄. It presents the optimal levels of other parameters and the reaction of optimized parameters for the maximum trehalose.