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Immunotherapy: It pays to be persistent.
- Source :
- Nature Reviews Cancer; Dec2008, Vol. 8 Issue 12, p906-907, 2p, 1 Color Photograph
- Publication Year :
- 2008
-
Abstract
- The article reports on a study by Malcolm Brenner and colleagues that one way to enhance the costimulation of T cells and increase their survival and anti-tumor activity in vivo, is to express a tumor-specific-antigen receptor in cytotoxic T lymphocytes (CTLs) that are specific for Epstein-Barr virus (EBV) because these cells are extensively costimulates by EBV-infected B cells in vivo.
- Subjects :
- EPSTEIN-Barr virus
LYMPHOCYTES
T cells
ANTIGENS
ONCOGENIC DNA viruses
Subjects
Details
- Language :
- English
- ISSN :
- 1474175X
- Volume :
- 8
- Issue :
- 12
- Database :
- Complementary Index
- Journal :
- Nature Reviews Cancer
- Publication Type :
- Academic Journal
- Accession number :
- 35387394
- Full Text :
- https://doi.org/10.1038/nrc2554