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Genetic thrombophilia variants and risk for preeclampsia among American Indians.
- Source :
- Hypertension in Pregnancy; Mar2009, Vol. 28 Issue 1, p85-94, 10p, 4 Charts
- Publication Year :
- 2009
-
Abstract
- <bold>Objective: </bold>To determine the prevalence of thrombophilic genetic variants in an American Indian population and determine if they are associated with preeclampsia.<bold>Methods: </bold>A total of 87 cases, 165 controls and an additional 75 population-based controls were genotyped for two thrombophilic polymorphisms.<bold>Results: </bold>The allelic prevalence of the factor V Leiden and 20210 G/A prothrombin variants in this population was 2.1% and 0.5% respectively. No statistically significant associations between these genetic variants and preeclampsia were found.<bold>Conclusion: </bold>The prevalence of thrombophilic variants is of possible public health significance for other morbidity; but perhaps not in relation to preeclampsia. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10641955
- Volume :
- 28
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Hypertension in Pregnancy
- Publication Type :
- Academic Journal
- Accession number :
- 36188918
- Full Text :
- https://doi.org/10.1080/10641950802419887