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Antigen presentation: Parasite hijacking.
- Source :
- Nature Reviews Immunology; Mar2009, Vol. 9 Issue 3, p150-151, 2p, 1 Illustration
- Publication Year :
- 2009
-
Abstract
- The article reports on the study which focuses on Toxoplasma gondii tachyzoites that have infected host cells residing in the parasitophorous vacuole (PV). Researchers have generated a system which will permit them to trace antigen-specific T-cell responses to T. gondii-derived antigens espousing phagocytosis of infected cells or dead parasites. It reveals that T. gondii-derived antigens are cross-presented by major histocompatibility complex (MHC) class I molecules to CD8<superscript>+</superscript> cells.
Details
- Language :
- English
- ISSN :
- 14741733
- Volume :
- 9
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Nature Reviews Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 36636686
- Full Text :
- https://doi.org/10.1038/nri2512