Back to Search
Start Over
Interleukin-12 family members and type I interferons in Th17-mediated inflammatory disorders.
- Source :
- Allergy; May2009, Vol. 64 Issue 5, p702-709, 8p, 2 Diagrams
- Publication Year :
- 2009
-
Abstract
- Cytokines produced by antigen-presenting cells govern the fate of helper T-cell responses. Herein, we review the impact of interleukin (IL)-23 and IL-27 on the outcome of T-helper (Th) 17 cell responses and discuss their impact in the pathogenesis of T-cell-mediated inflammatory disorders of autoimmune or allergic origin. We then discuss how type I interferons might influence the course of autoimmune diseases by tipping the balance between IL-12 family members. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01054538
- Volume :
- 64
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Allergy
- Publication Type :
- Academic Journal
- Accession number :
- 37266483
- Full Text :
- https://doi.org/10.1111/j.1398-9995.2009.02039.x