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Intracellular Life of Coxiella burnetii in Macrophages.
- Source :
- Annals of the New York Academy of Sciences; May2009, Vol. 1166, p55-66, 12p
- Publication Year :
- 2009
-
Abstract
- Coxiella burnetii, the agent of Q fever, is an obligate intracellular bacterium that is considered a potential biological weapon of category B. C. burnetii survives within myeloid cells by subverting receptor-mediated phagocytosis and preventing phagosome maturation. The intracellular fate of C. burnetii also depends on the functional state of myeloid cells. This review describes the mechanisms used by C. burnetii to circumvent uptake and trafficking events, and the role of cytokines on C. burnetii survival in myeloid cells. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00778923
- Volume :
- 1166
- Database :
- Complementary Index
- Journal :
- Annals of the New York Academy of Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 40307521
- Full Text :
- https://doi.org/10.1111/j.1749-6632.2009.04515.x