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Stathmin and Tubulin Expression and Survival of Ovarian Cancer Patients Receiving Platinum Treatment With and Without Paclitaxel.

Authors :
Dan Su
Smith, Stephanie M.
Preti, Mario
Schwartz, Peter
Rutherford, Thomas J.
Menato, Guido
SaveriovDanese
Shenglin Ma
Yu, Herbert
Katsaros, Dionyssios
Source :
Cancer (0008543X); 6/1/2009, Vol. 115 Issue 11, p2453-2463, 11p, 3 Charts, 5 Graphs
Publication Year :
2009

Abstract

The article presents a study which analyzed the tubulin and stathmin expression in ovarian tumors and their associations with treatment response and survival. It indicates that high stathmin expression was associated with diseases progression and overall survival of patients and notes that the association was independent of such disease stage. The findings supports the hypothesis that stathmin may interfere with paclitaxel treatment that will leads to poor prognosis.

Details

Language :
English
ISSN :
0008543X
Volume :
115
Issue :
11
Database :
Complementary Index
Journal :
Cancer (0008543X)
Publication Type :
Academic Journal
Accession number :
41548830
Full Text :
https://doi.org/10.1002/cncr.24282