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The twin spot generator for differential Drosophila lineage analysis.
- Source :
- Nature Methods; Aug2009, Vol. 6 Issue 8, p600-602, 3p, 3 Diagrams
- Publication Year :
- 2009
-
Abstract
- In Drosophila melanogaster, widely used mitotic recombination–based strategies generate mosaic flies with positive readout for only one daughter cell after division. To differentially label both daughter cells, we developed the twin spot generator (TSG) technique, which through mitotic recombination generates green and red twin spots that are detectable after the first cell division as single cells. We propose wide applications of TSG to lineage and genetic mosaic studies. [ABSTRACT FROM AUTHOR]
- Subjects :
- CELL proliferation
CELL growth
DROSOPHILA
CYTOLOGICAL techniques
CELL division
Subjects
Details
- Language :
- English
- ISSN :
- 15487091
- Volume :
- 6
- Issue :
- 8
- Database :
- Complementary Index
- Journal :
- Nature Methods
- Publication Type :
- Academic Journal
- Accession number :
- 43750052
- Full Text :
- https://doi.org/10.1038/nmeth.1349