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Enantioselective Michael addition of malononitrile to chalcones catalyzed by a simple quinine–Al(OiPr)3complex: a simple method for the synthesis of a chiral 4H-pyran derivativeElectronic supplementary information (ESI) available: Experimental procedures and analytical and spectral data of products . See DOI: 10.1039/b908632c

Authors :
Shi, Jian
Wang, Min
He, Ling
Zheng, Ke
Liu, Xiaohua
Lin, Lili
Feng, Xiaoming
Source :
Chemical Communications; Aug2009, Vol. 2009 Issue 31, p4711-4713, 3p
Publication Year :
2009

Abstract

Enantioselective Michael addition of malononitrile to chalcones was catalyzed by a simple quinine and Al(OiPr)3complex and products were obtained in good ee as well as high yields, which facilitated the asymmetric synthesis of a biologically active 4H-pyran compound. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
2009
Issue :
31
Database :
Complementary Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
43980224
Full Text :
https://doi.org/10.1039/b908632c