Destruxin production of Metarhizium anisopliae under carbon and nitrogen exhaustion.

The article presents a research paper that clarifies the impact of glucose and nitrogen exhaustion on destruxins (dtx) biosynthesis in Metarhizium anisopliae variant anisopliae. It discusses the influence of carbon and nitrogen exhaustion in the production and growth of dtx. It reveals that oxygen availability highly affects dtx production; however asserts that its production is lower in shake flasks than in bioreactors with controlled aeration of one volume per volume per minute (vvm).