Forum. Rodent tumors of urinary bladder, renal cortex, and thyroid gland in IARC Monographs evaluations of carcinogenic risk to humans.

The article discusses the highlights of an advisory meeting held by a group of experts in Lyon, France in November 1997, which explored the comparative pathology, biology and natural occurrence of tumors in rodents and in humans, as well as summarizes the evaluations that were made by an October 1998 Working Group that were based on the meeting's findings. Certain aromatic amines have been found to cause bladder carcinoma in humans and to cause cancers in rodents at some sites that do not always include the urinary bladder.