Immunoadsorption onto protein A induces remission in severe systemic lupus erythematosus.

Background. Reduction of pathological autoantibodies and circulating immune complexes can be useful in the treatment of autoimmune disease. Plasmapheresis has been shown to reduce autoantibody levels in systemic lupus erythematosus (SLE), but its effect on patients' outcome was not better compared with conventional immunosuppression in the past. [ABSTRACT FROM PUBLISHER]