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Pregnancy outcome of women transfused during pregnancy with blood products inadvertently obtained from donors treated with acitretin.
- Source :
- Journal of Obstetrics & Gynaecology; Nov2009, Vol. 29 Issue 8, p694-697, 4p, 2 Charts
- Publication Year :
- 2009
-
Abstract
- We assessed the pregnancy outcome of nine women inadvertently transfused with acitretin-contaminated blood products in South Korea. A total of 18 women matched to cases by age, gravidity, and singleton- or twin-pregnancy, and who were transfused with blood products not contaminated with acitretin, was also recruited. There were nine babies born in the case group. No differences (p > 0.05) were observed between cases and controls in the gestational age at delivery (38.3 ± 1.6 weeks vs 37.8 ± 2.2 weeks), birth weight (3,146 ± 874 g vs 3,106 ± 568 g), rate of pre-term deliveries (22.2% vs 11.1%) and rate of low birth weight (<2,500 g) (33.3% vs 16.7%). There was no case of malformation or neurological abnormalities born in either group. In conclusion, inadvertent exposure to acitretin-contaminated blood products was not associated with adverse pregnancy outcomes, probably because of the removal of acitretin and etretinate during the manufacturing process of blood products. [ABSTRACT FROM AUTHOR]
- Subjects :
- PREGNANCY
BLOOD
PREGNANT women
NEWBORN infants
PARITY (Obstetrics)
TRETINOIN
Subjects
Details
- Language :
- English
- ISSN :
- 01443615
- Volume :
- 29
- Issue :
- 8
- Database :
- Complementary Index
- Journal :
- Journal of Obstetrics & Gynaecology
- Publication Type :
- Academic Journal
- Accession number :
- 44746868
- Full Text :
- https://doi.org/10.3109/01443610903177128