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Influence of NOS1 on Verbal Intelligence and Working Memory in Both Patients With Schizophrenia and Healthy Control Subjects.

Authors :
Donohoe, Gary
Walters, James
Morris, Derek W.
Quinn, Emma M.
Judge, Róisín
Norton, Nadine
Giegling, Ina
Hartmann, Annette M.
Möller, Hans-Jürgen
Muglia, Pierandrea
Williams, Hywel
Moskvina, Valentina
Peel, Rosemary
O'Donoghue, Therese
Owen, Michael J.
O'Donovan, Michael C.
Gill, Michael
Rujescu, Dan
Corvin, Aiden
Source :
Archives of General Psychiatry; Oct2009, Vol. 66 Issue 10, p1045-1054, 10p, 2 Charts, 2 Graphs
Publication Year :
2009

Abstract

The article presents a study which examines the impact of nitric oxide synthase 1 (NOS1) gene to cognition of schizophrenic patients and healthy control subjects. It states that the study used several methodologies such as the genotyping of Irish and German patients, assessment cognitive functioning, and statistical analyses. Results show that NOS1 genotype on verbal intelligence quotient (IQ) affects the Irish patient. It concludes the association between NOS1 and cognition.

Details

Language :
English
ISSN :
0003990X
Volume :
66
Issue :
10
Database :
Complementary Index
Journal :
Archives of General Psychiatry
Publication Type :
Academic Journal
Accession number :
44970789
Full Text :
https://doi.org/10.1001/archgenpsychiatry.2009.139