Stereoselective synthesis of trans-β-lactams by palladium-catalysed carbonylation of vinyl aziridinesThis article is part of a ChemComm ‘Catalysis in Organic Synthesis’ web-theme issue showcasing high quality research in organic chemistry. Please see our website (http://www.rsc.org/chemcomm/organicwebtheme2009) to access the other papers in this issue.Electronic supplementary information (ESI) available: Full experimental and characterisation. See DOI: 10.1039/b920564k

Authors :: Fontana, Francesco
Tron, Gian Cesare
Barbero, Nekane
Ferrini, Serena
Thomas, Stephen P.
Aggarwal, Varinder K.
Source :: Chemical Communications; 1/14/2010, Vol. 46 Issue 2, p267-269, 3p
Publication Year :: 2010
Abstract: The palladium-catalysed carbonylation of vinyl aziridines can give either the trans- or cis-β-lactam preferentially or even the δ-lactam simply by adjusting the reaction parameters ([Pd], [CO], temperature). [ABSTRACT FROM AUTHOR]