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Multiple single-nucleotide polymorphisms (SNPs) in the Japanese population in six candidate genes for long QT syndrome.
- Source :
- Journal of Human Genetics; 2001, Vol. 46 Issue 3, p158, 5p
- Publication Year :
- 2001
-
Abstract
- Abstract We report here 20 single-nucleotide polymorphisms (SNPs), including 15 novel ones, in six genes that are considered to be candidates for long QT syndrome (LQTS): 2 SNPs in KCNB1, 3 in KCND3, 3 in KCNJ11, 7 in ABCC9, 3 in ADRB1, and 2 in SLC18A2. We also examined their allelic frequencies in a Japanese sample population of LQTS-affected and nonaffected individuals. These data will be useful for genetic association studies designed to investigate acquired arrhythmias. [ABSTRACT FROM AUTHOR]
- Subjects :
- GENETIC polymorphisms
DISEASES
ARRHYTHMIA
Subjects
Details
- Language :
- English
- ISSN :
- 14345161
- Volume :
- 46
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Journal of Human Genetics
- Publication Type :
- Academic Journal
- Accession number :
- 4688458
- Full Text :
- https://doi.org/10.1007/s100380170106