T cell responses: mTOR mixes up a recipe for success.

The article discusses the study which determines the crucial role of mammalian target of rapamycin (mTOR) in the blending of the signals from the three factors to determine the effector versus memory CD8+ T cells responses. The researchers involve the antigen, co-stimulation for T cell activation and cytokine stimulation to determine the result. Researchers then show that mTOR is the crucial point of integration in CD8+ T cells for signals that programme effector versus memory differentiation.