Back to Search
Start Over
Statin Users Without an APOE-ℇ4 Allele have Increased Insulin Resistance.
- Source :
- Journal of Alzheimer's Disease; 2010, Vol. 19 Issue 4, p1149-1153, 5p, 1 Chart, 1 Graph
- Publication Year :
- 2010
-
Abstract
- The present study examined the relationships among statin use, APOE genotype, and insulin resistance as measured by the homeostasis model assessment of insulin resistance (HOMA-IR) in healthy older adults. APOE ℇ4- (i.e., not having an ℇ4 allele) statin users had higher HOMA-IR values compared with ℇ4+/statin users (p=0.0169), and with non-users who were ℇ4- (p=0.0003) or ℇ4+ (p=0.0006). These results suggest that statin use may modulate insulin levels for individuals without an APOE ℇ4 allele. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13872877
- Volume :
- 19
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Journal of Alzheimer's Disease
- Publication Type :
- Academic Journal
- Accession number :
- 48706341
- Full Text :
- https://doi.org/10.3233/JAD-2010-1319