Quinine-Resistant Malaria in Traveler Returning from Senegal, 2007.

Authors :: Pradines, Bruno
Pistone, Thierry
Ezzedine, Khaled
Briolant, Sébastien
Bertaux, Lionel
Receveur, Marie-Catherine
Parzy, Daniel
Millet, Pascal
Rogier, Christophe
Malvy, Denis
Source :: Emerging Infectious Diseases; Mar2010, Vol. 16 Issue 3, p546-548, 3p, 1 Chart
Publication Year :: 2010
Abstract: We describe clinical and parasitologic features of in vivo and in vitro Plasmodium falciparum resistance to quinine in a nonimmune traveler who returned to France from Senegal in 2007 with severe imported malaria. Clinical quinine failure was associated with a 50% inhibitory concentration of 829 nmol/L. Increased vigilance is required during treatment follow-up. [ABSTRACT FROM AUTHOR]