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Comparison of99mTc-Technegas SPECT with133Xe dynamic SPECT in pulmonary emphysema.
- Source :
- Annals of Nuclear Medicine; Sep1997, Vol. 11 Issue 3, p201-206, 6p
- Publication Year :
- 1997
-
Abstract
- This study was undertaken to compare axial images of<superscript>99m</superscript>Tc-Technegas SPECT (Technegas) with those of<superscript>133</superscript>Xe gas dynamic SPECT in patients with pulmonary emphysema. There were 20 patients, 19 males and 1 female. All patients except one ex-smoker were heavy smokers with a mean age of 68.1 years. For Technegas scintigraphy, the patients inhaled 505 MBq<superscript>99m</superscript>Tc-Technegas in several tidal volume breaths in the supine position without breath holding. For<superscript>133</superscript>Xe gas scintigraphy, the patients inhaled 370 MBq<superscript>133</superscript>Xe gas.<superscript>133</superscript>Xe gas dynamic SPECT was performed in the equilibrium phase for the last minute of the 3 minute inhalation in a closed circuit, and in the washout phase for 6 minutes of inhalation in a semi-closed circuit, by means of a gamma camera with dual detectors (Picker model Prism 2000). Abnormal findings included heterogeneity, defects and hot spots on Technegas images and on retention images taken 3 minutes after<superscript>133</superscript>Xe gas washout. In 2 of 20 patients, the degree of abnormal findings on Technegas images depended on the area of<superscript>133</superscript>Xe gas retention in the washout phase. In 3 patients, the degrees of abnormal findings on both Technegas SPECT and<superscript>133</superscript>Xe gas dynamic SPECT images were equivalent. In the remaining 15 patients, more detailed findings and a greater area were shown by Technegas SPECT than<superscript>133</superscript>Xe gas dynamic SPECT. We conclude that in patients with pulmonary emphysema Technegas SPECT can demonstrate ventilation impairment more easily than<superscript>133</superscript>Xe gas dynamic SPECT. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09147187
- Volume :
- 11
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Annals of Nuclear Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 49559302
- Full Text :
- https://doi.org/10.1007/BF03164764