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Gingival Mucinous Adenocarcinoma of a Minor Salivary Gland.
- Source :
- Journal of Periodontology; Apr2010, Vol. 81 Issue 4, p626-631, 6p, 3 Diagrams, 1 Chart
- Publication Year :
- 2010
-
Abstract
- Background: A 47-year-old male non-smoker with a history of psoriasis sought a consultation because of a painless, hard-on-palpation, 1-cm exophytic lesion with a smooth and speckled surface located on the hard palate adjacent to tooth #12. The radiologic examination revealed no bone destruction. The lesion was clinically diagnosed as a fibrous hyperplasia or chronic pyogenic granuloma. Methods: The lesion was surgically removed, fixed in 10% neutral buffered formalin for 24 hours, and, following common practice, embedded in paraffin. Sections, 4 µm thick, were stained with hematoxylin and eosin, periodic acid-Schiff, and alcian blue, pH 2.5. An immunohistochemical study was also performed. Results: A definitive diagnosis of a mucinous adenocarcinoma (MAC), a very rare, high-grade malignancy tumor that more frequently appears in the elderly, was made. With the definitive diagnosis of an MAC of the palate, the upper-left premolars were extracted using a box osteotomy, and the surgical wound was reconstructed with a Bichat fat-pad flap. After a 6-month follow-up, no recurrence or cervical metastases were identified. Conclusions: An MAC of a minor salivary gland may arise as a gingival exophytic lesion with a clinical appearance similar to a pyogenic granuloma. The existence of a light speckled pattern on the surface of the lesion indicates that an incisional biopsy is needed before surgical treatment to make possible a definitive diagnosis. To avoid delays in diagnosis and erroneous clinical approaches to exophytic gingival lesions, periodontists and practitioners should routinely perform a pathologic analysis to confirm the diagnosis when dealing with these kinds of lesions. [ABSTRACT FROM AUTHOR]
- Subjects :
- ADENOCARCINOMA
GINGIVAL diseases
TUMORS
ORAL cancer
HYPERPLASIA
PSORIASIS
Subjects
Details
- Language :
- English
- ISSN :
- 00223492
- Volume :
- 81
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Journal of Periodontology
- Publication Type :
- Academic Journal
- Accession number :
- 49717574
- Full Text :
- https://doi.org/10.1902/jop.2009.090370