4-Hydroxy-2-quinolones. 47. Synthesis and Diuretic Activity of (2H-1,2,4-Benzothiadiazine-1,1-dioxide-3-yl)methylamides of 1-R-4-Hydroxy-2-oxoquinoline-3-carboxylic Acids.

With the aim of investigating the relationship between chemical structure and biological activity we have synthesized and studied the effect of (2H-1,2,4-benzothiadiazine-1,1-dioxide-3-yl)methylamides of 1-R-4-hydroxy-2-oxoquinoline-3-carboxylic acids on kidney urinary output. [ABSTRACT FROM AUTHOR]