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Long-term operation of continuous high cell density culture of Saccharomyces cerevisiae with membrane filtration and on-line cell concentration monitoring.
- Source :
- Bioprocess & Biosystems Engineering; Aug1999, Vol. 21 Issue 2, p97-100, 4p
- Publication Year :
- 1999
-
Abstract
- An internal membrane-filtration bioreactor system with periodic fouling removal and on-line cell measurement was employed for long-term continuous ethanol production from glucose in order to prove its performance and practicality. The bioreactor system developed in this study was successfully operated for 2 months with no problems in the maintenance of filtration flux. The maximum productivity obtained in this study was about 13 g/l-h which was ca. 3.3 times higher than that obtained in a conventional chemostat without cell retention by membrane. In another run of continuous culture, the laser turbidimeter used for the on-line monitoring of cell concentration showed a stable performance for 45 days without sensitivity loss due to fouling. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 16157591
- Volume :
- 21
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Bioprocess & Biosystems Engineering
- Publication Type :
- Academic Journal
- Accession number :
- 50190897
- Full Text :
- https://doi.org/10.1007/PL00009070