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A role of PDGFRalpha in basal cell carcinoma proliferation.

Authors :
Jingwu Xie
Aszterbaum, Michelle
Xiaoli Zhang
Bonifas, Jeannette M.
Zachary, Christopher
Epstein, Ervin
McCormick, Frank
Source :
Proceedings of the National Academy of Sciences of the United States of America; 7/31/2001, Vol. 98 Issue 16, p9255, 5p, 9 Diagrams, 4 Graphs
Publication Year :
2001

Abstract

Examines the role of platelet-derived growth factor receptor alpha (PDGFR alpha) in basal cell carcinoma proliferation. Activation of the hedgehog pathway; Molecular basis of neoplastic effect; Functional up-regulation of PDGFR alpha; Importance of PDGFR alpha increased expression mechanism.

Details

Language :
English
ISSN :
00278424
Volume :
98
Issue :
16
Database :
Complementary Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
5040240
Full Text :
https://doi.org/10.1073/pnas.151173398