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Tandem Michael addition/intramolecular isocyanide [3 + 2] cycloaddition: highly diastereoselective one pot synthesis of fused oxazolinesElectronic supplementary information (ESI) available: Detailed experimental procedures and analytical data. CCDC 753607(2a) and CCDC 761982(6b). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c001617a
- Source :
- Chemical Communications; May2010, Vol. 46 Issue 19, p3357-3359, 3p
- Publication Year :
- 2010
-
Abstract
- A base-catalyzed tandem Michael addition/intramolecular isocyanide [3 + 2] cycloaddition of ethyl isocyanoacetate and Michael acceptors with tethered carbonyl groups is described. This reaction leads to the formation of fused oxazolines in a highly diastereoselective manner under very mild conditions. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 46
- Issue :
- 19
- Database :
- Complementary Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 50519770
- Full Text :
- https://doi.org/10.1039/c001617a