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Association between Albuminuria, Carotid Atherosclerosis, Arterial Stiffness, and Peripheral Arterial Disease in Korean Type 2 Diabetic Patients.
- Source :
- Kidney & Blood Pressure Research; 2010, Vol. 33 Issue 2, p111-118, 8p, 3 Charts
- Publication Year :
- 2010
-
Abstract
- Background: To evaluate the association between albuminuria, carotid atherosclerosis, arterial stiffness, and peripheral arterial disease (PAD) in Korean type 2 diabetic patients. Methods: In total, 673 type 2 diabetic patients registered with the public health center participated. Following an overnight fast, venous blood and urine samples were collected and analyzed. The carotid intima-media thickness (IMT), amount of carotid plaque, brachial ankle pulse wave velocity (baPWV), and the ankle-brachial index of each patient were also assessed. Results: Albuminuria was significantly associated with PAD (odds ratio (OR) 2.33; 95% confidence interval (CI) 1.28–4.25 for normoalbuminuria vs. microalbuminuria and OR 3.28; 95% CI 1.40–7.66 for normoalbuminuria vs. macroalbuminuria), but not with carotid plaque. The mean baPWV differed significantly according to the level of albumin relative to the creatinine ratio (1,764.79, 1,778.98, and 2,001.33, respectively; p < 0.001), while no significant difference was observed in the mean IMT value (0.73, 0.74, and 0.72, respectively; p = 0.399). Conclusions: Albuminuria was significantly associated with baPWV and PAD, but not with carotid plaque or CCA-IMT, in Korean type 2 diabetic patients. Copyright © 2010 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14204096
- Volume :
- 33
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Kidney & Blood Pressure Research
- Publication Type :
- Academic Journal
- Accession number :
- 51176998
- Full Text :
- https://doi.org/10.1159/000313594