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Odanacatib, a Cathepsin-K Inhibitor for Osteoporosis: A Two-Year Study in Postmenopausal Women With Low Bone Density.

Authors :
Bone, Henry G.
McClung, Michael R
Roux, Christian
Recker, Robert R.
Eisman, John A.
Verbruggen, Nadia
Hustad, Carolyn M.
DaSilva, Carolyn
Santora, Arthur C.
Ince, B. Avery
Source :
Journal of Bone & Mineral Research; May2010, Vol. 25 Issue 5, p937-947, 11p, 1 Diagram, 3 Charts, 2 Graphs
Publication Year :
2010

Abstract

The article discusses a study which examined the role of the cathepsin K inhibitor odanacatib in osteoporosis. The clinical trial involved postmenopausal women with low bone mineral density (BMD). The clinical trial found that two years of weekly treatment with odanacatib was generally well tolerated by the patients. The drug also increased lumbar spine and total hip BMD in the patients.

Details

Language :
English
ISSN :
08840431
Volume :
25
Issue :
5
Database :
Complementary Index
Journal :
Journal of Bone & Mineral Research
Publication Type :
Academic Journal
Accession number :
51325697
Full Text :
https://doi.org/10.1359/jbmr.091035