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Influence of an Extremely Low Frequency Magnetic Field (ELF-EMF) on Antioxidative Vitamin E Properties in AT478 Murine Squamous Cell Carcinoma Culture In Vitro.
- Source :
- International Journal of Toxicology (Sage); 2010, Vol. 29 Issue 2, p221-230, 10p
- Publication Year :
- 2010
-
Abstract
- This study examines the effects of vitamin E and an extremey low frequency electromagnetic field (ELF-EMF) and their combination in different time intervals of exposure of vitamin E (tocopherol) on the AT478 murine squamous cell carcinoma line. This study provides insight into the influence of correlations between ELF-EMF and vitamin E supplementation on antioxidant enzyme activity in malignant cells in vitro. Following vitamin E treatment, activity of the antioxidant enzymes is increased in an exposure-dependent manner compared with the untreated group. Application of ELF-EMF alone or with vitamin E increases both superoxide dismutase isoenzymes and glutathione peroxidase activities in comparison to the control group. The results suggest that ELF-EMF alters antioxidative activities of vitamin E in AT478 tumor cells. This study confirms the role of vitamin E in decreasing susceptibility to lipid peroxidation in AT478 tumor cells. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10915818
- Volume :
- 29
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- International Journal of Toxicology (Sage)
- Publication Type :
- Academic Journal
- Accession number :
- 52620722
- Full Text :
- https://doi.org/10.1177/1091581809352011