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Genetic Variation in the RANKL/RANK/OPG Signaling Pathway Is Associated With Bone Turnover and Bone Mineral Density in Men.
- Source :
- Journal of Bone & Mineral Research; Aug2010, Vol. 25 Issue 8, p1830-1838, 9p, 2 Diagrams, 2 Charts
- Publication Year :
- 2010
-
Abstract
- The article discusses a study which determined the link of genetic variation in the RANKL/RANK/OPG signaling pathway with bone turnover and bone mineral density (BMD) in men. The researchers selected pairwise tag single-nucleotide polymorphisms (SNPs) in RANKL, RANK and OPG and their flanking regions. The results of the study suggest that genetic variation in the RANKL/RANK/OPG signaling pathway has an effect on bone turnover and BMD in European men.
Details
- Language :
- English
- ISSN :
- 08840431
- Volume :
- 25
- Issue :
- 8
- Database :
- Complementary Index
- Journal :
- Journal of Bone & Mineral Research
- Publication Type :
- Academic Journal
- Accession number :
- 53493967
- Full Text :
- https://doi.org/10.1002/jbmr.78